Adverse Drug Reactions and Immunopathological Mechanisms — PHAR4009

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PHAR4009 Pharmacology Honours · University of the Witwatersrand · Winter 2026

PHAR4009 Pharmacology Honours (Wits) quiz covering adverse drug reactions and immunopathological mechanisms, including Type A through D classifications, hypersensitivity reactions, drug-induced conditions like Stevens-Johnson syndrome and warfarin-induced skin necrosis, and clinical management of adverse responses.

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Create multiple choice practice questions based on these anki cards and their answers. The format must be as follows: 1 set of questions, with 50 questions, with all sections mixed together in the questions. There must be 5 options per question. 3 options can be correct with the remaining 2 incorrect, or 3 options can be incorrect with the remaining 2 correct. The sequence of options in each question must be in a random order. Include a memo.

Question 1 of 50

Which of the following characteristics correctly defines a Type A (augmented) adverse drug reaction?

It typically emerges years after completion of therapy due to irreversible accumulation.
It is predictable, dose-related, and can be alleviated by reducing the dosage.
It is an immunologically mediated hypersensitivity reaction seen only in atopic patients.
It is an unpredictable, bizarre effect that occurs independently of the administered dose.

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